Is Chemoprevention Overrated or Underfunded?

Is the brain overrated?

Determinism Is Overrated

Our accelerating computational demand and the rise of multicore hardware have made parallel programs, especially shared-memory multithreaded programs, increasingly pervasive and critical. Yet, these programs remain extremely difficult to write, test, analyze, debug, and verify. Conventional wisdom has attributed these difficulties to nondeterminism, and researchers have recently dedicated much ...

Hidden Staphylococcus aureus Carriage: Overrated or Underappreciated?

Staphylococcus aureus is a persistent companion bacterial species in one-third of humankind. Reservoirs include the nasal and nasopharyngeal cavities, skin, and gastrointestinal (GI) tract. Despite earlier claims that colonization of individuals is caused by clonal organisms, next-generation sequencing (NGS) has revealed that resident type heterogeneity is not exceptional. Carriage, whether ove...

The European Commission’s Power: Overrated or Justified?

For decades the bureaucratic and legislative power of the European Commission has interested scholars of EU studies. Yet, relatively little data are known about the exact division of power of the European Commission in legislative affairs apart from case studies (Cini, 2000; Schmidt, 2000). This paper presents analyses of qualitative and quantitative data to analyse how powerful some experts co...

The Synaptic Vesicle Cycle: Is Kissing Overrated?

In this issue of Neuron, Granseth et al. re-examine the mechanism of endocytosis at hippocampal synapses using a new optical reporter, sypHy. They conclude that only a single slow mode of endocytosis operates at this synapse and that retrieval after physiological stimuli is largely, if not solely, dominated by the clathrin-mediated pathway. These conclusions dispute previous assertions that "ki...